Do people want to know if they are at risk for Alzheimer's disease?

Public release date: 10-Jul-2012
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Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100 x2156
Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, July 9, 2012Genetic tests exist to identify risk for the rare inherited form of early-onset Alzheimer's disease (AD) and to predict susceptibility to the more common, late-onset form of AD, but do people want to know, and how do they react? The answers can be found in the article published in Genetic Testing and Molecular Biomarkers, a peer-reviewed journal from Mary Ann Liebert, Inc. The article is available free on the Genetic Testing and Molecular Biomarkers website.

"This article addresses a major disease of tremendous impact on increasing numbers of people and documents the large psychological component that physicians and genetic counselors must be ready to address." says Kenneth I. Berns, MD, PhD, Editor-in-Chief of Genetic Testing and Molecular Biomarkers, and Director of the University of Florida's Genetics Institute, College of Medicine, Gainesville, FL.

In the article "To Know or Not to Know: An Update of the Literature on the Psychological and Behavioral Impact of Genetic Testing for Alzheimer Disease Risk," B. Rahman and a team of researchers from Australia review the latest studies on whether people at risk for early-onset familial AD want to know their genetic profile and actually undertake testing, and how they tend to respond to the results. They also evaluate the attitudes of the general population and people with a family history of late-onset AD toward testing for disease risk factors and what motivates them to undergo genetic testing.

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About the Journal

Genetic Testing and Molecular Biomarkers is an authoritative peer-reviewed journal published 10 times per year in print and online that reports on all aspects of genetic testing, including molecular and biochemical based tests and varied clinical situations; ethical, legal, social, and economic aspects of genetic testing; and issues concerning effective genetic counseling. Tables of contents and a free sample issue may be viewed on the Genetic Testing and Molecular Biomarkers website.

About the Publisher

Mary Ann Liebert, Inc. is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Human Gene Therapy and OMICS. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 70 journals, books, and newsmagazines is available at Mary Ann Liebert, Inc..

Mary Ann Liebert, Inc. 140 Huguenot St., New Rochelle, NY 10801-5215
Phone: (914) 740-2100 (800) M-LIEBERT Fax: (914) 740-2101 www.liebertpub.com

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 10-Jul-2012
[ | E-mail | Share ]

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100 x2156
Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, July 9, 2012Genetic tests exist to identify risk for the rare inherited form of early-onset Alzheimer's disease (AD) and to predict susceptibility to the more common, late-onset form of AD, but do people want to know, and how do they react? The answers can be found in the article published in Genetic Testing and Molecular Biomarkers, a peer-reviewed journal from Mary Ann Liebert, Inc. The article is available free on the Genetic Testing and Molecular Biomarkers website.

"This article addresses a major disease of tremendous impact on increasing numbers of people and documents the large psychological component that physicians and genetic counselors must be ready to address." says Kenneth I. Berns, MD, PhD, Editor-in-Chief of Genetic Testing and Molecular Biomarkers, and Director of the University of Florida's Genetics Institute, College of Medicine, Gainesville, FL.

In the article "To Know or Not to Know: An Update of the Literature on the Psychological and Behavioral Impact of Genetic Testing for Alzheimer Disease Risk," B. Rahman and a team of researchers from Australia review the latest studies on whether people at risk for early-onset familial AD want to know their genetic profile and actually undertake testing, and how they tend to respond to the results. They also evaluate the attitudes of the general population and people with a family history of late-onset AD toward testing for disease risk factors and what motivates them to undergo genetic testing.

###

About the Journal

Genetic Testing and Molecular Biomarkers is an authoritative peer-reviewed journal published 10 times per year in print and online that reports on all aspects of genetic testing, including molecular and biochemical based tests and varied clinical situations; ethical, legal, social, and economic aspects of genetic testing; and issues concerning effective genetic counseling. Tables of contents and a free sample issue may be viewed on the Genetic Testing and Molecular Biomarkers website.

About the Publisher

Mary Ann Liebert, Inc. is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Human Gene Therapy and OMICS. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 70 journals, books, and newsmagazines is available at Mary Ann Liebert, Inc..

Mary Ann Liebert, Inc. 140 Huguenot St., New Rochelle, NY 10801-5215
Phone: (914) 740-2100 (800) M-LIEBERT Fax: (914) 740-2101 www.liebertpub.com

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2012-07/mali-dpw071012.php

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Nova Product Wayns Records Double-Double in NBA Summer League Debut

For undrafted guard Maalik Wayns, the NBA Orlando Summer League is a great opportunity to impress the NBA scouts. Wayns got off to a good start today in his debut, as he scored 11 points and dished out 10 assists for the Orlando Magic in a 92-88 win over the Brooklyn Nets. He started the game, played 28 mins, shot 2-7 from the field and 7-9 from the line, while also committing 3 turnovers and notching 4 steals.

Although Maalik did not shoot well from the field, he got his teammates involved and got to the line, two crucial skills of being a point guard. The Magic will continue their summer league schedule with a contest against the Detroit Pistons at 3 PM tomorrow, July 10th.

Source: http://www.thenovablog.com/2012/7/9/3148065/nova-product-wayns-records-double-double-in-nba-summer-league-debut

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'Glee,' 'Archie' Crossover: Riverdale Gang Meeting New Directions

PHILADELPHIA -- The kids from Riverdale are no strangers to high school angst, worries about fitting in or music. Neither are the teens from "Glee."

Now, Archie, Betty, Veronica and resident boy genius Dilton Doiley will match wits ? and maybe a vocal or two ? with the likes of Finn Hudson, Kurt Hummel and Rachel Berry in the pages of "Archie Comics," said Jon Goldwater, the co-chief executive officer.

Goldwater unveiled the planned collaboration on Monday, ahead of Wednesday's start of Comic-Con in San Diego.

He said the crossover between the Fox show and the comic book is set for late this year or in early 2013, and is being written by Roberto Aguirre-Sacasa, one of the television show's writers. It features multiple characters from the long-running comic book and the Fox show now in its third year. Dan Parent is illustrating the story.

"I've become friendly with Roberto ? he's just a genius writer," said Goldwater, who met the playwright last year at New York Comic Con when he stopped by Archie Comic Publications Inc.'s booth. "He and I were shooting the breeze."

That visit sparked a friendship and, ultimately, the idea for the crossover.

"It turns out he's been a fan of Archie for years. His most recent Halloween costume? He was dressed as Archie!" Goldwater said.

For now, says Goldwater, the plot of the four-issue story arc in "Archie Comics" is a closely-held secret, but it does involve parallel dimensions, dancing and some serious singing, too.

It's also the latest step for the publisher, which has expanded its pop cultural offerings beyond just Jughead, Midge and Mr. Weatherbee.

In the past two years, Archie Comics has brought in an openly-gay character, Kevin Keller; been visited by the band Kiss; and seen Archie marry Valerie, the bassist for Josie and the Pussycats, and have a daughter with her.

"Those have reintroduced a lot of people back to `Archie,'" Goldwater said. "And it's opened a whole new world of people coming to `Archie' for the first time, too."

Goldwater said that in the course of his conversation with Aguirre-Sacasa it was evident both "Glee" and "Archie" had some common ground despite coming from decidedly different mediums, including a diverse array of characters, conditions and concerns.

"`Glee' is courageous in their story lines and how they represent their characters, how they represent the high school situation," he said, noting that it's similar in the world of Archie, too.

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Online:

Also on HuffPost:

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Source: http://www.huffingtonpost.com/2012/07/09/glee-archie-crossover-comic-book_n_1658723.html

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Roswell UFO Was Not Of This Earth And There Were ET Cadavers: Ex-CIA Agent Says

Happy anniversary, Roswell, N.M. It was 65 years ago today that the Roswell Daily Record blasted an infamous headline claiming local military officials had captured a flying saucer on a nearby ranch. And now, a former CIA agent says it really happened.

"It was not a damn weather balloon -- it was what it was billed when people first reported it," said Chase Brandon, a 35-year CIA veteran. "It was a craft that clearly did not come from this planet, it crashed and I don't doubt for a second that the use of the word 'remains' and 'cadavers' was exactly what people were talking about."

Brandon served as an undercover, covert operations officer in the agency's Clandestine Service for 25 years, where he was assigned missions in international terrorism, counterinsurgency, global narcotics trafficking and weapons smuggling. He spent his final 10 years of CIA service on the director's staff as the agency's first official liaison to the entertainment and publication industries. It was during this time, in the mid-1990s, that he walked into a special section of CIA headquarters in Langley, Va., called the Historical Intelligence Collection.

"It was a vaulted area and not everybody could get in it," Brandon told The Huffington Post. "One day, I was looking around in there and reading some of the titles that were mostly hand-scribbled summations of what was in the boxes. And there was one box that really caught my eye. It had one word on it: Roswell.

"I took the box down, lifted the lid up, rummaged around inside it, put the box back on the shelf and said, 'My god, it really happened!'"

What exactly did the box contain that had such a powerful impact on Brandon?

"Some written material and some photographs, and that's all I will ever say to anybody about the contents of that box," he said. "But it absolutely, for me, was the single validating moment that everything I had believed, and knew that so many other people believed had happened, truly was what occurred,"

None of this comes as a surprise to Stanton T. Friedman, a nuclear-physicist-turned-UFOlogist, who was the original civilian investigator of the Roswell UFO incident.

In the late 1970s, Friedman began to uncover former military eyewitnesses who had been involved with the original events that took place at Roswell in 1947.

Despite the fact that the military changed its story overnight, saying on July 8, 1947 that a flying disk had been captured but claiming on July 9 that a weather balloon had been recovered, Friedman's early investigative efforts prompted many Roswell witnesses to come forward and tell their stories. Numerous researchers have dug up more facts in the years since.

"It's been 65 years since things took place at Roswell," Friedman told HuffPost. "How much more widely known could it be -- everywhere I've spoken in the world, they ask about Roswell."

"What we really need now is the Woodward-Bernstein of the UFO world to bring out the disclosure," said Friedman. "Maybe Chase Brandon is a foresight of something going on.

"It's time for the retirement of the mythical part -- where we don't have all the pieces -- to be replaced by the true story of what happened, all the details, and we certainly don't have them."

Watch this video about Stanton Friedman's involvement with the Roswell UFO incident.

Brandon is currently promoting his book, "The Cryptos Conundrum," a science fiction story about the history of Earth, contact with extraterrestrials and imagined cataclysmic events on our planet.

He remains steadfast about the pieces of the Roswell puzzle he's willing to share, and he emphasizes there's no internal CIA policy that prevents him from revealing any details of what he saw in that box at the agency headquarters.

"Nobody tells any of us that we can't say anything about sources, methods, classified information having to do with working for the Central Intelligence Agency," Brandon said. "We all sign a secrecy agreement that says we understand we are forbidden to do that by law, and that is an inherent part of keeping and safeguarding what we do, how we do it, why we do it, out of national security concerns.

"I'm not reluctant to talk about it -- I won't talk about it. I'm telling you there was a box that had stuff in there having to do with Roswell, and I looked through it, and it validated everything I believed in, and that's all I have to say about it. I will go to my grave being mindful of the two hats that I wear: My personal one and the one that will forever reside on my head as a former CIA officer."

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Source: http://www.huffingtonpost.com/2012/07/08/roswell-ufo-cia-agent-chase-brandon_n_1657077.html

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Study suggests new screening method for sudden death in athletes

Public release date: 9-Jul-2012
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Contact: Jim Feuer
jim.feuer@cchmc.org
513-636-4656
Cincinnati Children's Hospital Medical Center

A new study suggests that echocardiography be included as part of screenings to help identify student athletes with heart problems that could lead to sudden death.

The Cincinnati Children's Hospital Medical Center study, presented recently at the annual meeting of the American Society of Echocardiography, suggests adding a modified echo to the current practice of taking an EKG, getting a family history and having a physical exam.

"EKG is a good tool, but may not be sensitive enough to catch problems that could lead to sudden death," says Michelle Grenier, MD, a physician at the Cincinnati Children's Heart Institute and one of the investigators of the study. "We found that an abbreviated echo is a fiscally responsible addition that will yield useful information when screening student athletes for structural heart disease and cardiomyopathies heart muscle diseases that are the major cause of sudden death in athletes."

Screening for risk of sudden death in athletes has long been a topic of controversy, in part because it is expensive and time consuming. Her study, however, indicates that a shortened echo may increase the sensitivity of finding heart defects in competitive athletes.

As part of an ongoing study, Dr. Grenier and colleagues at Cincinnati Children's recruited 85 teen athletes for a screening that included a health questionnaire, physical exam, EKG and a 15-image, modified echo that took nine minutes, on average, to obtain. Echoes that were considered abnormal were referred for a complete echo, where they were read by a cardiologist not involved in the study.

Ten of the participants (12 percent) had abnormal echoes when read in real-time and were referred for further assessment. These 10 participants had a normal history, physical exam and EKG. All preliminary diagnoses were later substantiated. The researchers found no additional heart problems, and all 10 echoes were later confirmed to be abnormal.

"The number of patients with asymptomatic, congenital heart disease was higher than expected, but the rate of cardiomyopathy the main cause of sudden death in athletes is probably closer to the published rate," says Dr. Grenier. "Our goal is to provide useful information to care providers, who may then better counsel athletes and their families on full participation in sports.

"The cost-effectiveness and impact on reducing the rate of sudden cardiac death aren't yet known, but the impact on quality of life in reassurance of cardiac health during exercise is priceless," she says.

###

---

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 9-Jul-2012
[ | E-mail | Share ]

Contact: Jim Feuer
jim.feuer@cchmc.org
513-636-4656
Cincinnati Children's Hospital Medical Center

A new study suggests that echocardiography be included as part of screenings to help identify student athletes with heart problems that could lead to sudden death.

The Cincinnati Children's Hospital Medical Center study, presented recently at the annual meeting of the American Society of Echocardiography, suggests adding a modified echo to the current practice of taking an EKG, getting a family history and having a physical exam.

"EKG is a good tool, but may not be sensitive enough to catch problems that could lead to sudden death," says Michelle Grenier, MD, a physician at the Cincinnati Children's Heart Institute and one of the investigators of the study. "We found that an abbreviated echo is a fiscally responsible addition that will yield useful information when screening student athletes for structural heart disease and cardiomyopathies heart muscle diseases that are the major cause of sudden death in athletes."

Screening for risk of sudden death in athletes has long been a topic of controversy, in part because it is expensive and time consuming. Her study, however, indicates that a shortened echo may increase the sensitivity of finding heart defects in competitive athletes.

As part of an ongoing study, Dr. Grenier and colleagues at Cincinnati Children's recruited 85 teen athletes for a screening that included a health questionnaire, physical exam, EKG and a 15-image, modified echo that took nine minutes, on average, to obtain. Echoes that were considered abnormal were referred for a complete echo, where they were read by a cardiologist not involved in the study.

Ten of the participants (12 percent) had abnormal echoes when read in real-time and were referred for further assessment. These 10 participants had a normal history, physical exam and EKG. All preliminary diagnoses were later substantiated. The researchers found no additional heart problems, and all 10 echoes were later confirmed to be abnormal.

"The number of patients with asymptomatic, congenital heart disease was higher than expected, but the rate of cardiomyopathy the main cause of sudden death in athletes is probably closer to the published rate," says Dr. Grenier. "Our goal is to provide useful information to care providers, who may then better counsel athletes and their families on full participation in sports.

"The cost-effectiveness and impact on reducing the rate of sudden cardiac death aren't yet known, but the impact on quality of life in reassurance of cardiac health during exercise is priceless," she says.

###

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2012-07/cchm-ssn070912.php

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Ballots burn as most of Benghazi votes

Hundreds of protesters burned ballots to demand greater representation although most residents of the Mediterranean city of Benghazi voted on Saturday in historic elections vowing to build a new Libya.

Gunfire echoed after around 200 demonstrators filled a major square in the eastern city, which was the cradle of last year's revolt that ousted dictator Moamer Kadhafi.

They were encircled by cars of supporters of the vote for a national assembly and later by at least a dozen military vehicles whose forces fired into the air in a show of strength.

But as soon as the armed forces left, the protesters began to attack the civilian cars, damaging several of them.

"We are the ones who started the rebellion and now nobody is bothered about us. Nobody wants to talk to us. All we are asking for is a proper democratic process," said one demonstrator, who gave his name as Fuad al-Obeidi.

"Let the constitution be written first then hold the elections with equal number of seats for every region. I have boycotted the election along with my family," the 32-year-old government employee told AFP.

Abduljawad Shadwan, a 49-year-old lecturer who supports the election process, condemned the protesters.

"I can understand their views but this is not the right way. We are building a new Libya and actions like these only deny the building of a new country," said Shadwan.

"But this will not stop the progress of Libya. The result of the election will be unprecedented. It will be historic," he added.

Elsewhere, gunmen attacked a polling station at Tulay Tala school in Benghazi Jadida in the city's southwest, destroying the ballot boxes and firing into the air before fleeing, according to witnesses.

"Around 60 men and some women stormed the school at around 1:00 pm (1100 GMT) before breaking the ballot boxes and stealing some election material," said Ahmed Saleh, an election observer at the school.

"Some armed men fired in the air. Some bullets hit the school building, shattering the glass. They were chanting 'Allahu akbar' (God is greatest)," he told AFP.

Earlier, voting was marred by attacks by protesters calling for greater representation at one polling centre in the city and some other parts of eastern Libya.

They forced the closure of several polling stations in areas outside Benghazi, but failed to dampen the enthusiasm of most of the city's residents to cast their ballot.

"I am voting today for a new Libya which we will create from the blood shed by our martyrs," said Abdel Jalil Mansur, who works at Benghazi airport.

"The blood of our martyrs will not go to waste," he said as he stepped out of Al-Hurriyah polling station in central Benghazi carrying his five-year-old daughter, Arwa, draped in the new Libyan flag.

Hueida Abdul Sheikh, a 47-year-old mother, was one of the first voters in Benghazi in the hope that the vote she cast will help build the future for her and her three children.

"I feel like my life has been wasted so far but now my children will have a better life. All they need is a push, and I believe the new leaders will give that push so that children can achieve their ambitions," she said.

Another voter, policeman Yussef Amer Ali, said he had voted for "peace and security" in the hope that "all Libyans will achieve their dreams in this new country."

Benghazi was the first city to rebel against the regime of Kadhafi, with protesters, inspired by the Arab Spring uprising in neighbouring Egypt and Tunisia, pouring out onto the streets in February 2011.

That initial protest in Libya's second-largest city spread rapidly to engulf the entire country. It ended with the capture and killing of Kadhafi on October 20 after a revolt supported by powerful NATO air cover.

On Saturday, groups of young men carrying machineguns were patrolling various streets, especially near polling centres, offering what they said was "protection to voters and voting centres."

But protesters demanding greater representation for eastern Libya, forcefully closed several polling stations.

Some voting centres were also shut in the eastern city of Ajdabiya, where a depot containing electoral material was torched earlier this week, an official in Benghazi told AFP.

Another official said voting was disrupted at oasis towns in southeastern Libya, including Jalo and Ojla, after federalism supporters prevented a plane carrying polling material from taking off.

Abdeljawad al-Badin, spokesman of the self-appointed Cyrenaica Council, said voters in Quba, near the town of Derna, were boycotting the electoral process altogether.

Interim leader Mustafa Abdel Jalil, who voted in his eastern home town of Al-Bayda, told AFP "we hope that our brothers in Benghazi will stay away from such problems and that the voting will go ahead as planned."

Source: http://news.yahoo.com/ballots-burn-most-benghazi-votes-003823540.html

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Video: Ex-football player starts camp for kids

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Source: http://nbcsports.msnbc.com/id/21134540/vp/48110309#48110309

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